ASGSB TWENTY-THIRD ANNUAL MEETING

October 25-28, 2007
Moffett Field, CA

 PROGRAM

 

SEARCH       Titles, Authors, and Abstracts

THURSDAY, October 25, 2007
12:00 Noon Registration Begins
7:30 PM ASGSB Governing Board Meeting
FRIDAY, October 26, 2007
7:30 AM Registration Opens
8:15   AM Opening Remarks and Welcome,   Chris Brown, Program Chair
SYMPOSIUM I

Astrobiology
8:30 to 12:15  (Friday, Oct. 26, 2007)
 Moderator:   David Morrison, Symposium Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
8:30 Opening Remarks David Morrison    
8:45 Astrobiological Exploration of the Surface of Mars D.J. Des Marais [1] 2
9:30 Survival of Microbes in Space: Experimental Tests of Panspermia

R.L. Mancinelli

 [2] 2
10:15 BREAK
10:45 Self-assembly Processes in the Prebiotic Environment D. Deamer [3] 2
11:30 Origins of Protein Functions in Cells A. Pohorille [4] 2
12:15 PM Lunch, Special Session and Committee Meetings
12:30 PM

Special Session on the International Space Station as a National Laboratory, Greg Schmidt, NASA Ames Research Center

CONCURRENT POSTERS I
Posters I-A.  Undergraduate Student Poster Competition

2:00 to 3:30 pm, (Friday, Oct. 26, 2007)
NOTE: Presenters are to be next to their posters the entire time.

POSTER # TITLE AUTHORS ABSTRACT # PAGE
A01 Examining the Early Response of Osteoclasts to Ionizing Radiation E.R. Anderson, J.S. Willey, J. Nagatomi, T.A. Bateman [5] 4
A03 Study of Phototropism in Arabidopsis thaliana in Microgravity on the ISS B.A. Butler, P. Kumar and J.Z. Kiss [6] 4
A05 Proton Irradiation Effects a Neurobehavioral Response in the Fruit Fly Drosophila Melanogaster I.M. Choi, M.E. Sanchez, O. Marcu, F. Selch, O. Inan, S. Bhattacharya [7] 4
A07 Directed Selection for CO2-Tolerant Cyanobacteria and Algae K.M. Crowell, C. Chan and D.J. Thomas [8] 4
A09 Partial Weight Suspension Effects On Gait Dynamics In Mice K.C. Gosselin, A.L. Harman, W.H. Tan and E.B. Wagner [9] 5
A11 Functional Analysis of Genes Expressed in Response to Light and Gavity Stimulation in Arabidopsis Root Tips J. Huang, R. Hammond, S. Hume, J. Dalal, C. Brown and H. Winter-Sederoff [10] 5
Posters I-B.  Graduate Student Poster Competition

2:00 to 3:30 pm, (Friday, Oct. 26, 2007)
NOTE: Presenters are to be next to their posters the entire time.
POSTER # TITLE AUTHORS ABSTRACT # PAGE
B01 Maximizing RNA Extraction From Plants Grown on the International Space Station A.J. Stimpson, R.S. Pereira and M.J. Correll [11] 8
B03 Bioconvection Patterns In Cultures Of A Calcifying Alga S.J. Chen and P.J. Duke [12] 8
B05 PKS1 is Involved in Red-Light-Based Positive Phototropism in Arabidopsis Roots M.L. Molas and J.Z. Kiss [13] 8
B07 Are the Responses of Adductor Longus Muscle to Gravitational Unloading in Wistar Hannover Rats Region-specific?  T. Ohira, X.D. Wang, M. Terada, F. Kawano, Y. Higo, N. Nakai, T. Ochiai, J. Gyotoku, N. Nishimoto and Y. Ohira [14] 8
B09 Role of the Actin Related Protein (ARP) 2/3 Complex in Gravitropism J.C. Reboulet, P. Kumar and J.Z. Kiss [15] 9
B11 Effects of Low-Energy X-rays on Trabecular Bone Loss in Mice L.C. Smith and T.A. Bateman [16] 9
B13 Simulated Microgravity Inhibits Proliferation of Malignant Glioma Cells M. Takeda, T. Okazaki, T. Magaki, A. Sasaki, S.L. Wu, Y. Kawahara, R. Yoshimoto, T. Manabe, T. Kajiume, L. Yuge and K. Kurisu [17] 9
B15 Responses of Back Muscle Fibers in Sprague-Dawley Rats to Spaceflight M. Terada, F. Kawano, H. Kume, T. Ohira, Y. Higo, Y. Nakajima, X.D. Wang, N. Nakai, W.E. Hinds and Y. Ohira [18] 9
B17 Black Bears (Ursus americanus) Maintain Muscle to Body Weight Ratio in Unloaded Soleus Muscle During Winter Hibernation J.M. Van Dyke, D.V. Baewer, B.D. Curry, S.R. Govindaraju, J.W. Bain, V. Vogel, M. Gappa, B. Kohn and D.A. Riley [19] 10
B19 Characterization of Hematopoietic Stem Cells Cultured in 3D-clinostat R. Yoshimoto, T. Kajiume, Y. Kawahara, A. Sasaki, S.L. Wu, T. Manabe, M. Takeda, T. Magaki and L. Yuge [20] 10

CONCURRENT POSTERS II
Posters II-A.  Undergraduate Student Poster Competition (continued)

3:30 to 5:00 pm, (Friday, Oct. 26, 2007)
NOTE: Presenters are to be next to their posters the entire time.
POSTER # TITLE AUTHORS ABSTRACT # PAGE
A02 Protein Expression in Glycine max Cells under Microgravity Conditions W.A. Kelly Jr., S.E. Kelly and J.V. Valluri [21] 12
A04 The Effects of Exogenous Hydrogen Peroxide on Cyanobacterial Antioxidant Mutants under Ambient and Primordial Conditions N. McCarthy, K. Marie Crowell and D.J. Thomas [22] 12
A06 Responses of Body Composition and Hematological and Muscular Properties of Meriones Unguiculatus to Gravitational Unloading Y. Nakajima, M. Terada, F. Kawano, H. Sumi, Y. Shimizu, T. Ohira, Y. Higo, X.D. Wang, N. Nakai and Y. Ohira [23] 12
A08 Microarray Analysis of Plants Grown on the International Space Station R.S. Pereira, A.J. Stimpson and M.J. Correll [24] 12
A10 Macrophage Colony Stimulating Factor Produces Increased Trabecular Bone Density and Turnover, Characteristic of an Anabolic Agent S.E. Riffle, Y.Y. Yuan and T.A. Bateman [25] 13
A12 Transcript Abundance of Lipogenic Enzymes Parallels Lipid Metabolism in the Mammary Gland of Rats Exposed to Altered Gravity during Pregnancy M.K. VanKlompenberg, O.V. Patel and K. Plaut [26] 13
A14 Effects of Low Dose Ionizing Radiation on Bone Metabolism in Rats L. Tirado, J.S. Willey and T.A. Bateman [27] 13
Posters II-B.  Graduate Student Poster Competition (continued)

3:30 to 5:00 pm, (Friday, Oct. 26, 2007)
NOTE: Presenters are to be next to their posters the entire time.
POSTER #     ABSTRACT # PAGE
B02 Characterizing Molecular Signaling Pathways During Hindlimb Suspension Induced Atrophy Followed by Voluntary Exercise A.M. Hanson, B.C. Harrison, L.S. Stodieck and V.L. Ferguson [28] 16
B04 Transcriptional Regulation of Changes in Growth, Cell Cycle, and Gene Expression of Saccharomyces cerevisiae Due to Changes in Buoyancy C.B. Coleman, P.L. Allen, J.M. Valles and T.G. Hammond [29] 16
B06 Microgravity Inhibits Neural Differentiation While Sustaining The Capability of Differentiation A. Sasaki, M. Takeda, T. Magaki, S.L. Wu, Y. Kawahara, R. Yoshimoto, T. Manabe, A. Boulenouar, T. Kajiume and L. Yuge [30] 16
B08 Bone Loss Following Proton Irradiation E.R. Bandstra, M.J. Pecaut, E.R. Anderson, J.S. Willey, F. De Carlo, S.R. Stock, D.S. Gridley, G.A. Nelson and T.A. Bateman [31] 16
B10 WISE-2005: Lower Body Negative Pressure Treadmill Exercise and Resistive Exercise Countermeasures Maintain Physiologic Function in Women during 60-days of Bed Rest B.R. Macias, S.M. Schneider, S.M.C. Lee, P. Guinet, S. Meuche, R.L. Hughson, S.M. Smith, S.R. Zwart, D.E. Watenpaugh and A.R. Hargens [32] 17
B12 Mars Gravity Biosatellite: Payload Design Plans Beyond PDR T.R.F. Fulford-Jones, M.L. Colbath, A.J. Gordhandas, E.B. Grosse and J.A. Hoffman [33] 17
B14 Increased Expression of Myostatin and its Receptor, Activin RIIb, after 14 Day Hindlimb Unloading in the Mouse B.J. Greybeck, D.L. Allen, A.M. Hanson, V.L. Ferguson and L.S. Stodieck [34] 17
B16 Early Mechanisms of Gravity-Sensing in Plants J. Hauslage, N. Greuel and M. Braun [35] 17
B18 The Effects of Microgravity on Stem Cell Differentiation S.E. Kelly, P.P. Claudio and J.V. Valluri [36] 18
B20 Long Term Effects of Heavy Ion Radiation on Bone Loss in Mice E.W. Livingston and T.A. Bateman [37] 18
B22 Disuse Exacerbates Suppression of Bone Formation with Administration of Low-Dose Antiresorptive Drugs S.A.J. Lloyd and T.A. Bateman [38] 18
B24 Simulated Microgravity Activates MAPK Pathways in Fibroblasts Cultured on Microgrooved Substrates W.A. Loesberg, X.F. Walboomers, J.J.W.A. Van Loon and J.A. Jansen [39] 18
EVENING EVENTS, Friday, October 26, 2007
5:00 Committee Meetings
6:30 RECEPTION
SATURDAY, October 27, 2007
SYMPOSIUM II

Science for Small Satellites

8:30 to 12:15, (Saturday, Nov. 4, 2006)
Moderator:    John Hines, Symposium Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
8:30 Opening Remarks John Hines    
9:00 A Small Payloads Program for Astrobiology J.D. Rummel [40] 20
9:30 Non-Exploration Life Sciences Research within NASA’s Exploration Systems Mission Directorate J. Cohen [41] 20
10:00 BREAK
10:30 Studying Space Effects on Microorganisms Autonomously: GeneSat, PharmaSat and the Future of Bio-nanosatellites M. Parra, M.R. McGinnis, A.J. Ricco, B. Yost and J.W. Hines [42] 20
11:00 Recoverable Satellite for Animal Research T. Ochiai, H. Matsumoto and K. Shimura [43] 20
11:30 US Participation in the Russian Bion-M1 Mission: An Overview M.G. Skidmore, R. Boyle and K.A. Souza [44] 21
12:00 Lunch, Special Session, and Committee Meetings
12:30 Special Session on Careers,  Thaddeus Fulford Jones, ASGSB Student Association President

CONCURRENT ORAL SESSIONS I and II
ORAL SESSION I

Spaceflight Results and Biotechnology

2:00 to 4:00 PM, (Saturday, October 27, 2007)
Moderator:    Paul Todd, Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
2:00 Ongoing Comparative Study of the Effects of Microgravity During Foton M2 and M3 on Cancellous Bone Mass in the Aquatic Newt Pleurodeles waltl and the Terrestrial Gecko Pachydactylus bibronii E. Almeida, N. Dvorchkin, R. Turner, R. Globus and N. Searby [45] 24
2:15 Small Satellite Platform for Automated Gene Expression Measurements A. Pohorille, A.J. Ricco, A. McShea, D. Danley and K. Schweighofer [46] 24
2:30 Maximizing RNA Extraction From Plants Grown on the International Space Station A.J. Stimpson, R.S. Pereira and M.J. Correll [47] 24
2:45 Space Flight Microgravity and Ground Proton Irradiation Induce an Immune Response and Tumorigenesis in the Fruit Fly, Drosophila melanogaster S. Bhattacharya, M.E. Sanchez, M. Lera, L. Higgins, E. Blazevic and O. Marcu [48] 24
3:00 WISE-2005: Lower Body Negative Pressure Treadmill Exercise and Resistive Exercise Countermeasures Maintain Physiologic Function in Women during 60-days of Bed Rest B.R. Macias, S.M. Schneider, S.M.C. Lee, P. Guinet, S. Meuche, R.L. Hughson, S.M. Smith, S.R. Zwart, D.E. Watenpaugh and A.R. Hargens [49] 25
3:15 Activation and Regulation of Monocyte Differentiation C-F. Li  and M. Hughes-Fulford [50] 25
3:30 3D Random Rotations Induce Apoptosis In Cultured Astrocytes M.A.  Masini, B. Uva, F. Strollo, P. Prato and F. Ricci [51] 25

CONCURRENT ORAL SESSIONS I and II
ORAL SESSION II

Plant and Stress - Gravity, Radiation and More

2:00 to 4:00 PM, (Saturday, October 27, 2007)
Moderator:    Gioia Massa, Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
2:00 Triple Traits Improvement in Genetic Engineering Tomatoes for Space Exploration M. Khodakovskaya, C. Brown, J.B. Freeman, L. Stodieck and H.W. Sederoff [52] 28
2:15 Knockouts of Either APY1 or APY2 Genes Suppress Root Gravitropism in Arabidopsis S.J. Roux, J. Zalawadia, J. Wu and T. Butterfield [53] 28
2:30 Bioconvection Patterns In Cultures Of A Calcifying Alga S.J. Chen and P.J. Duke [54] 28
2:45 Heat Shock Protein Expression in Response of Pea Seedlings to Altered Gravity L.Y. Kozeko, A.S. Talalaev and E.L. Kordyum [55] 28
3:00 Testing of the HELIAC 2 Plant Detection and Lighting System G.D. Massa, C.M. Bourget, R.C. Morrow and C.A. Mitchell [56] 29
3:15 A Synthetic Approach to Redesigning Plants to Survive in Inhospitable Environments: Overexpression of Pyrococcus Furiosus Superoxide Reductase in Arabidopsis Y. Im, C. Lowder, M. Ji, A.M. Lee, A.M. Grunden and W.F. Boss [57] 29
3:30 Seed Production Across the Gravity Continuum in Brassica and Arabidopsis M.E. Musgrave, A. Kuang, J. Allen, R. Darnell, R. Wagers-Hughes, E. Escobedo and J. Blasiak [58] 29
3:45 The Role of Nitric Oxide and cGMP as Downstream Signals for Transduction of Calcium Dependent Gravisensing M.L. Salmi, K.E. Morris, S.J. Roux and D.M. Porterfield [59] 29

CONCURRENT POSTERS III

4:00 to 5:30 pm, (Saturday, October 27, 2007)
NOTE: Presenters are to be next to their posters the entire time.
POSTER # TITLE AUTHORS ABSTRACT # PAGE
C01 Seed Production by Plants Grown in a Lunar Thermophotoperiod J. Blasiak and M.E. Musgrave [60] 32
C02 Plants as Countermeasures for Humans Living in Isolated or Extreme Environments Such as Long Term Space Flight G.E. Bingham, S.C. Bates, V.I. Gushin, A.Vinokhodova, J. Marquit and V.N. Sychev [61] 32
C03 Gravity Effects on Growth Form of Brassica rapa L. and Arabidopsis thaliana (L.) Heyn J. Allen, A. Kuang, M. Regan and M.E. Musgrave [62] 32
C04 Performance of Rapid Cycling Dwarf Arabidopsis Grown In a Lunar Light Regimen R.N. Bowman and G-S. Sun [63] 32
C05 Glucosinolate Production in Hypergravity in Brassica rapa R.L. Darnell, L.H. Levine, P.A. Bisbee, J. Allen and M.E. Musgrave [64] 33
C06 The Role of Phytochrome C in Tropisms P. Kumar, C.E. Montgomery and J.Z. Kiss [65] 33
C07 Effects of Cis- and Trans-Retinoic Acid on Growth and Gravitropic Responses in Maize Roots T.J. Mulkey [66] 33
C08 Biomedical Sample Return from ISS in the Post-Shuttle Period E.L. Hill, M. Krihak, D. Atchison, P. Dumars, A. Dave, C. Kundrot and D. Reiss-Bubenheim [67] 33
C09 Neurovestibular Adaptation in the Utricular Otolith Following Extended Periods of 3G Exposure and Re-adaptation to 1G R. Boyle, Y. Popova, J. Varelas, A. Mofrad and A. Kondrachuk [68] 34
C10 Chemical Sensation Modulated by High Gravity Stress at Different Growth Stage in Rats M. Kimoto, S. Takase, K. Toda and Y. Kumei [69] 34
C11 Role of the Vestibular System in the Regulation of Body Mass in Male and Female Rats T.M. Hoban-Higgins and C.A. Fuller [70] 34
C12 Molecular Bases of Muscle Atrophy in Mammals: Comparative Studies on Bats and Rats K. Lee, T. Gwag, W. Yoo, J.W. Lee, M. Byun and I. Choi [71] 34
C13 Geranylgeranylaceton Increases Protein Content and Heat Shock Protein 72 Expression in Skeletal Muscle Cells K. Goto, S. Morioka, T. Naito, A. Kojima, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira and T. Yoshioka [72] 35
C14 Responses of Protein Expression to Cardiotoxin-induced Muscle Injury F. Kawano, M. Terada, N. Nakai, T. Ohira, Y. Higo, N. Nishimoto and Y. Ohira [73] 35
C15 Effects of Inhibited Neural and/or Mechanical Stimuli on the Water Content and Dry Weight in Rat Hindlimb Muscles X.D. Wang, M. Danda, M. Terada, F. Kawano, T. Ohira, Y. Higo, Y. Nakajima, N. Nakai, K. Goto and Y. Ohira [74] 35
C16 A New Paradigm for Environmental Limits of Life: Finding Clues from Unknown Proteins J.D. Ng, R.C. Hughes, M. Byrnes, M. Davis and G. Podila [75] 35
C17 Testing the Oxygen Paradox with Antioxidant-Deficient Cyanobacteria M. Eubanks, J. Boling, M. Crowell, T. McSpadden, C. Rector, C.L. Schuchardt, C.J. Spurlock, J. Warrington and D.J. Thomas [76] 36
C18 Multiuser Experiment Facilities for the Japanese Experiment Module “Kibo” M. Takaoki [77] 36
C19 Bacterial Response to Modeled Microgravity - A Comparison Between Genotypic and Phenotypic Responses M.A. Juergensmeyer, E.M. Mobley and E.A. Juergensmeyer [78] 36
C20 The Differentiation of Myoblast is Regulated by Gravity Y. Kawahara, R. Yoshimoto, A. Sasaki, S.L. Wu, T. Manabe, T. Kajiume, M. Takeda, T. Magaki and L. Yuge [79] 36
C21 Concomitant Cytokine Secretion and Amino Acid Metabolism Alterations in Human Leucocytes Subjected to Microgravity Analog and  Cortisol Treatment In Vitro P.N. Uchakin, S.M. Smith, O.N. Uchakina and B.W. Tobin [80] 37
C22 The Effects of Microgravity on the Metastasis of Cancer Cells E.E. Williams, N. Miller, E. Ancel, C. Manarinjara, S. Moore, C. Sczamarski, D. Tollaver and S. Ullah [81] 37
C23 Effect of Simulated Weightlessness on the Induction of ERK2 by Fluid Shear Stress in MG-63 Osteosarcoma Cells S. Zhang, B. Wang, Z. Yang and X.Q. Sun [82] 37
C24 Dementia Astronautica: A Possible Outcome of Long-Duration Space Missions? P.M. Cummings and A. Obenaus [83] 37
C25 Three-Dimensional Organization and Enhanced Function of HepG2 Liver Cells Cultured in a Reduced Gravity Environment T.T. Chang and M. Hughes-Fulford [84] 38
C26 Radiation Biology Educator Guide J. Rask, B.J. Navarro, C. Elland and W. Vercoutere [85] 38
C27 SlimeSat (Space Laboratory for Investigations of Microbial Ecophysiology): A Proposal for a New Platform for the Investigation of the Effects of Variable Gravity and Space Radiation on Microbial Ecophysiology B.M. Bebout, E.D. Fleming, A.E. Frisbee, L.E. Prufert-Bebout, J.C. Rask, A.J. Ricco, F. Selch, S.P. Worden and B. Yost [86] 38
Saturday Evening, October 27, 2007

6:00
 
BANQUET/BUSINESS MEETING/AWARDS PRESENTATION

Banquet Speaker:   Seth Shostak, “When Will We Find ET, and What If We Do?”
9:30 STUDENT MIXER
SUNDAY, October 28, 2007
7:00 Governing Board Meeting
SYMPOSIUM III

Space Radiation Biology

8:30 to 12:15, (Sunday, October 28, 2007)
Moderator:    Paul Todd, Symposium Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
8:30 Space Radiation Health Research: Narrowing the Uncertainties in Exploration Risk P. Todd  [87]  40
9:00 Space Radiation Carcinogenesis: Reducing the Uncertainties R.L. Ullrich   [88]   40
9:45 BREAK
10:15 Neurological Effects of Exposure to Galactic Cosmic Rays G.A. Nelson   [89]   40
11:00 Acute Affects of Solar Proton Storms Combined with Space Flight Factors M.S. Mendonca, C.M. Orschell, H. Chin-Sinex, S.B. Klein, J. Farr, P.E. Sokol, A. Constance and P. Todd   [90]   40
11:45 Panel Questions and Answers
12:05 LUNCH
ORAL SESSION III

Space Physiology and Animal Development

1:30 to 3:30 PM, (Sunday, October 28, 2007)
 Moderator:   Bill Landis, Chair
TIME TITLE AUTHORS ABSTRACT # PAGE
1:30 Increased Filamentous Growth of Candida albicans in Simulated Microgravity L.E. Hyman, S.M. Altenburg. Y. Stypula, J. Ant and S. Nielsen-Preiss [91] 42
1:45 Effects of Simulated Microgravity on Swimbladder Development in the Zebrafish (Danio rerio) R.P. Croll, B.W. Lindsey, T.C. Dumbarton, G.N. Robertson and F.M. Smith. [92] 42
2:00 Characterizing Molecular Signaling Pathways During Hindlimb Suspension Induced Atrophy Followed by Voluntary Exercise A.M. Hanson, B.C. Harrison, L.S. Stodieck and V.L. Ferguson [93] 42
2:15 Neuronal Activities in Rat Hippocampus at Altered Gravity and 5HT Modulation Y. Kumei, J. Zeredo, T. Ikeda, H. Suzuki, M. Kimoto and K. Toda [94] 42
2:30 Iron Ion Irradiation Alters Adhesiveness of Vascular Endothelium D.F. Kucik, S. Khaled, K. Gupta, X. Wu, T. Yu, P. Chang and J.H.S. Kabarowski [95] 43
2:45 Gene Expression and Structure of Cultured Osteoblasts Subjected to Increased Gravity W.J. Landis, R. Jacquet, E. Lowder, K.J. Hodgens, J. Rask, D. Morgan, T. Shaw, J. Dwyer, T. Purcell, R. Globus and M. Rubin [96] 43
3:00 Gravity Plays a Key Role in Postnatal Development of Heart Rate Variability S. Nagaoka, C. Miyasaka, M. Shida, Y. Eno and Y. Ohira [97] 43
3:15 Effects of L-NNA on Arterial Contractile Responses of Abdominal Aortic Rings in Hindlimb Unweighting Rats J. Ma, X.L. Ren, J.X. Bao and H. Tang [98] 43

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